THE STRESS RELIEF CENTER

Subtitle

Fluoride

 

Fluoride is the ionic form of fluorine. The latter is widely available in nature in the form of fluoride minerals. The Merck Manual of Medical Information explains that most of the body?S fluoride is contained in in teeth and bones, and that small amounts of fluoride can make teeth more resistant to the acid that leads to cavities.

 

The general population is exposed to fluorides in the air and in food, but the main source is found in drinking water. Fluorine, as sodium fluoride, is contained in most municipal drinking water supplies in the United States and has been credited by the Centers for Disease Control and Prevention (CDC, U.S.A.) as ?one of the 10 greatest achievements in public health during the 20th century.? Community water fluoridation was first implemented in the United States in 1945, after recognizing that fluoride hardens tooth enamel.

 

However, an excess accumulation of fluoride in the body can lead to demineralization of bone and tooth enamel, to a toxic condition called fluorosis. Bony changes, characterized by osteosclerosis, exostoses of the spine, and genu valgum, usually are seen only after prolonged high intake of fluoride in adults. These changes occur due to the fact that fluoride is not biodegradable and it accumulates in the body and bones resulting in a toxic or poisoning effect.

 


 

Fluoride and Toxicity

 

The Merck Manual also discusses issues of the toxicity of fluoride. Excess accumulation of fluoride, fluorosis, occurs in teeth and bones in proportion to the level and duration of fluoride intake. Dental fluorosis is most evident in permanent teeth that develop during high fluoride intake. The earliest changes are chalky-white, irregularly distributed patches on the surface of the enamel. Over time, these patches become stained yellow or brown, producing a mottled appearance. Severe fluorosis weakens the enamel, pitting its surface.

 

The accumulation of fluoride in bones causes a condition known as skeletal fluorosis. In rare cases, consuming too much fluoride over a long period of time can result in dense but weak bones, bone spurs on the spine, and crippling due to calcification of ligaments.

 

The ongoing debate about the benefits of water fluoridation has been vigorous regarding the risk versus the benefit. Recent studies seem to suggest that the beneficial effects of fluoride are achieved through topical use and not through ingestion. Many Western European countries have rejected water fluoridation. In Belgium (a country which does not fluoridate its drinking water), a study commissioned by the health ministry found that excessive use of fluoride products increased the risk of osteoporosis and could damage the nervous system. As a result, in August 2002, Belgium became the first country in the world to prohibit fluoride supplements (fluoride chewing gum, tablets and drops). They did not, however, ban fluoride-containing toothpastes at that time because of the topical benefits in the prevention of tooth decay.

 

The potential danger regarding fluoride-containing toothpastes appears to be the accidental ingestion of fluoride due to inadvertently swallowing the paste and the absorption of fluoride via the mucous membrane (lining of the mouth) and tongue. A milligram can be absorbed in as little as two brushings. That equates to one plus milligrams of absorbed fluoride per day (Keeping in mind that the fastest method of administering stimulant drugs during a cardiac attack is sub-lingually -- under the tongue.). Swallowed or not, anyone using a fluoridated toothpaste will absorb at least this much, and some of us more. Young children are at the higher risk because they are more likely to swallow fluoride-containing toothpastes and rinses -- if not properly supervised by a parent or guardian.

 

Due to this concern, the Food and Drug Administration (FDA, U.S.A.) requires the following warning statement on the packaging of all fluoride-containing toothpastes:

 

 
?Warning: Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.?
 

 

Our extensive exposure to fluoride, in our water and food chain, has lead some medical professionals, scientists, and dentists to recommend the elimination of fluoride from the public water supply, and to avoid using fluoridated toothpastes.

 

The Dangers of Fluoride and Fluoridation
The Dangers of Fluoride and Fluoridation

By Michael Schachter M.D., F.A.C.A.M.

 

Approximately half of the United States' drinking water supply is fluoridated in an attempt to reduce dental cavities in children. Is this state of affairs justified? Is it safe?

Most Americans are unaware of the dangers of ingesting fluoride. Most dentists, physicians and scientists are unaware of the dangers of fluoride and water fluoridation. According to a 1988 article in the prestigious Chemical and Engineering News, scientific voices of opposition to fluoridation have been suppressed, since 1950 when the U.S. Public Health Service first endorsed fluoridation. Power tactics including threats, ridicule and frank censorship aimed at scientists and clinicians knowledgeable about fluoridation have prevented the truth about fluoride to be disseminated to the science world as well as to the public. Whenever a public agency is charged with objectively evaluating the safety of a procedure while at the same time endorsing and recommending it, a serious conflict of interest is set up. This is exactly the position of the U.S. Public Health Service for the past 44 years.

Facts About Fluoride

So, what are some of the facts about fluoride? According to the handbook, Clinical Toxicology of Commercial Products, fluoride is more poisonous than lead and just slightly less poisonous than arsenic. It is a cumulative poison that accumulates in bone over the years. According to the Physicians Desk Reference, "in hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema, or urticaria. Gastric distress, headache, and weakness have also been reported. These hypersensitive reactions usually disappear promptly after discontinuation of the fluoride."

From 1990 to 1992, the Journal of the American Medical Association published three separate articles linking increased hip fracture rates to fluoride in the water. In the March 22, 1990 issue of the New England Journal of Medicine, Mayo Clinic researchers reported that fluoride treatment of osteoporosis increased hip fracture rate and bone fragility.

A study by Procter and Gamble showed that as little as half the amount of fluoride used to fluoridate public water supplies resulted in a sizable and significant increase in genetic damage. Epidemiology research in the mid-1970's by the late Dr. Dean Burk, head of the cytochemistry division of the National Cancer Institute, indicated that 10,000 or more fluoridation-linked cancer deaths occur yearly in the United States. In 1989, the ability of fluoride to transform normal cells into cancer cells was confirmed by Argonne National Laboratories. Results released in 1989 of studies carried out at the prestigious Batelle Research Institute showed that fluoride was linked to a rare form of liver cancer in mice, oral tumors and cancers in rats, and bone cancer in male rats. Since 1991, the New Jersey Department of Health found that the incidence of osteosarcoma, a type of bone cancer, was far higher in young men exposed to fluoridated water as compared to those who were not.

In addition to the well documented toxic effects of fluoride, fluoride even at dosages of 1 part per million, found in artificially fluoridated water, can inhibit enzyme systems, damage the immune system, contribute to calcification of soft tissues, worsen arthritis and, of course, cause dental fluorosis in children. These are unsightly white, yellow or brown spots that are found in teeth exposed to fluoride during childhood. In 1993, the Subcommittee on Health Effects of Ingested Fluoride of the National Research Council admitted that 8% to 51% and sometimes up to 80% of the children living in fluoridated areas have dental fluorosis. Malnourished people, particularly children, usually targeted for fluoridation, are at greater risks to experience fluoride's harmful effects.

Surprisingly, the most recent studies do not even show that water fluoridation is effective in reducing tooth decay. In the largest U.S. Study of fluoridation and tooth decay, United States Public Health Service dental records of over 39,000 school children, ages 5-17, from 84 areas around the United States showed that the number of decayed, missing, and filled teeth per child was virtually the same in fluoridated and non-fluoridated areas. Dr. John Colquhoun, former Chief Dental Officer of the Department of Health for Auckland, New Zealand, investigated tooth decay statistics from about 60,000 12 to 13 year old children and showed that fluoridation had no significant effect on tooth decay rate.

Given all of this scientific information, what is behind this push for universal fluoridation? Prior to 1945, fluoride was properly regarded as an environmental pollutant. It was responsible for many lawsuits against industries, such as the aluminum industry and the phosphate fertilizer industry, whose waste products contain large quantities of fluoride. This fluoride destroyed crops and animals, leading to the lawsuits. The limited public view was that fluoride was an environmental pollutant that needed to be reduced or eliminated from the environment.

As a result of clever public relations campaigns, fluoride was transformed from an environmental pollutant to an essential nutrient necessary for producing healthy teeth. The science was poor, but the P.R. Campaign was great. Being against fluoride was like being against motherhood or apple pie. Industries not only made millions from selling this environmental pollutant to water companies and toothpaste companies, but more importantly, it saved billions of dollars that would be required to clean up this environmental pollutant.

So, what can you do to protect yourself from fluoride? 

First, avoid fluoridated water. Much of the metropolitan area, including New York City water is artificially fluoridated. Boiling water removes chlorine, but concentrates fluoride. Water filters do not remove fluoride, unless there is a reverse osmosis component. Children should avoid fluoridated vitamins and fluoride treatments at the dentist. Everyone should avoid fluoridated toothpaste. The concentration of fluoride in water is 1 ppm, in toothpaste 1,000 ppm and in fluoride dental rinses 10,000 ppm. Work on your legislators to get fluoride out of the water supplies. 

 

© 1996 Michael B. Schachter M.D.
50 Reasons to Oppose Fluoridation
50 Reasons to Oppose Fluoridation
Updated April 12, 2004

by Paul Connett, PhD
Professor of Chemistry
St. Lawrence University
Canton, NY 13617

 

1) Fluoride is not an essential nutrient (NRC 1993 and IOM 1997). No disease has ever been linked to a fluoride deficiency. Humans can have perfectly good teeth without fluoride.

2) Fluoridation is not necessary. Most Western European countries are not fluoridated and have experienced the same decline in dental decay as the US (See data from World Health Organization in Appendix 1, and the time trends presented graphically at http://www.fluoridealert.org/who-dmft.htm ). The reasons given by countries for not fluoridating are presented in Appendix 2.)

3) Fluoridation's role in the decline of tooth decay is in serious doubt. The largest survey ever conducted in the US (over 39,000 children from 84 communities) by the National Institute of Dental Research showed little difference in tooth decay among children in fluoridated and non-fluoridated communities (Hileman 1989). According to NIDR researchers, the study found an average difference of only 0.6 DMFS (Decayed Missing and Filled Surfaces) in the permanent teeth of children aged 5-17 residing in either fluoridated or unfluoridated areas (Brunelle and Carlos, 1990). This difference is less than one tooth surface! There are 128 tooth surfaces in a child's mouth. This result was not shown to be statistically significant. In a review commissioned by the Ontario government, Dr. David Locker concluded:

"The magnitude of [fluoridation's] effect is not large in absolute terms, is often not statistically significant and may not be of clinical significance" (Locker 1999).

4) Where fluoridation has been discontinued in communities from Canada, the former East Germany, Cuba and Finland, dental decay has not increased but has actually decreased (Maupome 2001; Kunzel and Fischer,1997,2000; Kunzel 2000 and Seppa 2000).

5) There have been numerous recent reports of dental crises in US cities (e.g. Boston, Cincinnati, New York City) which have been fluoridated for over 20 years. There appears to be a far greater (inverse) relationship between tooth decay and income level than with water fluoride levels.

6) Modern research (e.g. Diesendorf 1986; Colquhoun 1997, and De Liefde, 1998) shows that decay rates were coming down before fluoridation was introduced and have continued to decline even after its benefits would have been maximized. Many other factors influence tooth decay. Some recent studies have found that tooth decay actually increases as the fluoride concentration in the water increases (Olsson 1979; Retief 1979; Mann 1987, 1990; Steelink 1992; Teotia 1994; Grobleri 2001; Awadia 2002 and Ekanayake 2002).

7) The Centers for Disease Control and Prevention (CDC 1999, 2001) has now acknowledged the findings of many leading dental researchers, that the mechanism of fluoride's benefits are mainly TOPICAL not SYSTEMIC. Thus, you don't have to swallow fluoride to protect teeth. As the benefits of fluoride (if any exist) are topical, and the risks are systemic, it makes more sense, for those who want to take the risks, to deliver the fluoride directly to the tooth in the form of toothpaste. Since swallowing fluoride is unnecessary, there is no reason to force people (against their will) to drink fluoride in their water supply. This position was recently shared by Dr. Douglas Carnall, the associate editor of the British Medical Journal. His editorial appears in Appendix 3.

8) Despite being prescribed by doctors for over 50 years, the US Food and Drug Administration (FDA) has never approved any fluoride product designed for ingestion as safe or effective. Fluoride supplements are designed to deliver the same amount of fluoride as ingested daily from fluoridated water (Kelly 2000).

9) The US fluoridation program has massively failed to achieve one of its key objectives, i.e. to lower dental decay rates while holding down dental fluorosis (mottled and discolored enamel), a condition known to be caused by fluoride. The goal of the early promoters of fluoridation was to limit dental fluorosis (in its mildest form) to 10% of children (NRC 1993, pp. 6-7). A major US survey has found 30% of children in optimally fluoridated areas had dental fluorosis on at least two teeth (Heller 1997), while smaller studies have found up to 80% of children impacted (Williams 1990; Lalumandier 1995 and Morgan 1998). The York Review estimates that up to 48% of children in optimally fluoridated areas worldwide have dental fluorosis in all forms and 12.5% with symptoms of aesthetic concern (McDonagh, 2000).

10) Dental fluorosis means that a child has been overdosed on fluoride. While the mechanism by which the enamel is damaged is not definitively known, it appears fluorosis may be a result of either inhibited enzymes in the growing teeth (Dan Besten 1999), or through fluoride's interference with G-protein signaling mechanisms (Matsuo 1996). In a study in Mexico, Alarcon-Herrera (2001) has shown a linear correlation between the severity of dental fluorosis and the frequency of bone fractures in children.

11) The level of fluoride put into water (1 ppm) is up to 200 times higher than normally found in mothers' milk (0.005 – 0.01 ppm) (Ekstrand 1981; Institute of Medicine 1997). There are no benefits, only risks, for infants ingesting this heightened level of fluoride at such an early age (this is an age where susceptibility to environmental toxins is particularly high).

12) Fluoride is a cumulative poison. On average, only 50% of the fluoride we ingest each day is excreted through the kidneys. The remainder accumulates in our bones, pineal gland, and other tissues. If the kidney is damaged, fluoride accumulation will increase, and with it, the likelihood of harm.

13) Fluoride is very biologically active even at low concentrations. It interferes with hydrogen bonding (Emsley 1981) and inhibits numerous enzymes (Waldbott 1978).

14) When complexed with aluminum, fluoride interferes with G-proteins (Bigay 1985, 1987). Such interactions give aluminum-fluoride complexes the potential to interfere with many hormonal and some neurochemical signals (Strunecka & Patocka 1999, Li 2003).

15) Fluoride has been shown to be mutagenic, cause chromosome damage and interfere with the enzymes involved with DNA repair in a variety of cell and tissue studies (Tsutsui 1984; Caspary 1987; Kishi 1993 and Mihashi 1996). Recent studies have also found a correlation between fluoride exposure and chromosome damage in humans (Sheth 1994; Wu 1995; Meng 1997 and Joseph 2000).

16) Fluoride forms complexes with a large number of metal ions, which include metals which are needed in the body (like calcium and magnesium) and metals (like lead and aluminum) which are toxic to the body. This can cause a variety of problems. For example, fluoride interferes with enzymes where magnesium is an important co-factor, and it can help facilitate the uptake of aluminum and lead into tissues where these metals wouldn't otherwise go (Mahaffey 1976; Allain 1996; Varner 1998).

17) Rats fed for one year with 1 ppm fluoride in their water, using either sodium fluoride or aluminum fluoride, had morphological changes to their kidneys and brains, an increased uptake of aluminum in the brain, and the formation of beta amyloid deposits which are characteristic of Alzheimers disease (Varner 1998).

18) Aluminum fluoride was recently nominated by the Environmental Protection Agency and National Institute of Environmental Health Sciences for testing by the National Toxicology Program. According to EPA and NIEHS, aluminum fluoride currently has a "high health research priority" due to its "known neurotoxicity" (BNA, 2000). If fluoride is added to water which contains aluminum, than aluminum fluoride complexes will form.

19) Animal experiments show that fluoride accumulates in the brain and exposure alters mental behavior in a manner consistent with a neurotoxic agent (Mullenix 1995). Rats dosed prenatally demonstrated hyperactive behavior. Those dosed postnatally demonstrated hypoactivity (i.e. under activity or "couch potato" syndrome). More recent animal experiments have reported that fluoride can damage the brain (Wang 1997; Guan 1998; Varner 1998; Zhao 1998; Zhang 1999; Lu 2000; Shao 2000; Sun 2000; Bhatnagar 2002; Chen 2002, 2003; Long 2002; Shivarajashankara 2002a, b; Shashi 2003 and Zhai 2003) and impact learning and behavior (Paul 1998; Zhang 1999, 2001; Sun 2000; Ekambaram 2001; Bhatnagar 2002).

20) Five studies from China show a lowering of IQ in children associated with fluoride exposure (Lin Fa-Fu 1991; Li 1995; Zhao 1996; Lu 2000; and Xiang 2003a, b). One of these studies (Lin Fa-Fu 1991) indicates that even just moderate levels of fluoride exposure (e.g. 0.9 ppm in the water) can exacerbate the neurological defects of iodine deficiency.

21) Studies by Jennifer Luke (2001) showed that fluoride accumulates in the human pineal gland to very high levels. In her Ph.D. thesis Luke has also shown in animal studies that fluoride reduces melatonin production and leads to an earlier onset of puberty (Luke 1997).

22) In the first half of the 20th century, fluoride was prescribed by a number of European doctors to reduce the activity of the thyroid gland for those suffering from hyperthyroidism (over active thyroid) (Stecher 1960; Waldbott 1978). With water fluoridation, we are forcing people to drink a thyroid-depressing medication which could, in turn, serve to promote higher levels of hypothyroidism (underactive thyroid) in the population, and all the subsequent problems related to this disorder. Such problems include depression, fatigue, weight gain, muscle and joint pains, increased cholesterol levels, and heart disease.

It bears noting that according to the Department of Health and Human Services (1991) fluoride exposure in fluoridated communities is estimated to range from 1.6 to 6.6 mg/day, which is a range that actually overlaps the dose (2.3 - 4.5 mg/day) shown to decrease the functioning of the human thyroid (Galletti & Joyet 1958). This is a remarkable fact, particularly considering the rampant and increasing problem of hypothyroidism in the United States (in 1999, the second most prescribed drug of the year was Synthroid, which is a hormone replacement drug used to treat an underactive thyroid). In Russia, Bachinskii (1985) found a lowering of thyroid function, among otherwise healthy people, at 2.3 ppm fluoride in water.

23) Some of the early symptoms of skeletal fluorosis, a fluoride-induced bone and joint disease that impacts millions of people in India, China, and Africa , mimic the symptoms of arthritis (Singh 1963; Franke 1975; Teotia 1976; Carnow 1981; Czerwinski 1988; DHHS 1991). According to a review on fluoridation by Chemical & Engineering News, "Because some of the clinical symptoms mimic arthritis, the first two clinical phases of skeletal fluorosis could be easily misdiagnosed" (Hileman 1988). Few if any studies have been done to determine the extent of this misdiagnosis, and whether the high prevalence of arthritis in America (1 in 3 Americans have some form of arthritis - CDC, 2002) is related to our growing fluoride exposure, which is highly plausible. The causes of most forms of arthritis (e.g. osteoarthritis) are unknown.

24) In some studies, when high doses of fluoride (average 26 mg per day) were used in trials to treat patients with osteoporosis in an effort to harden their bones and reduce fracture rates, it actually led to a HIGHER number of fractures, particularly hip fractures (Inkovaara 1975; Gerster 1983; Dambacher 1986; O’Duffy 1986; Hedlund 1989; Bayley 1990; Gutteridge 1990. 2002; Orcel 1990; Riggs 1990 and Schnitzler 1990). The cumulative doses used in these trials are exceeded by the lifetime cumulative doses being experienced by many people living in fluoridated communities.

25) Nineteen studies (three unpublished, including one abstract) since 1990 have examined the possible relationship of fluoride in water and hip fracture among the elderly. Eleven of these studies found an association, eight did not. One study found a dose-related increase in hip fracture as the concentration of fluoride rose from 1 ppm to 8 ppm (Li 2001). Hip fracture is a very serious issue for the elderly, as a quarter of those who have a hip fracture die within a year of the operation, while 50 percent never regain an independent existence (All 19 of these studies are referenced as a group in the reference section).

26) The only government-sanctioned animal study to investigate if fluoride causes cancer, found a dose-dependent increase in cancer in the target organ (bone) of the fluoride-treated (male) rats (NTP 1990). The initial review of this study also reported an increase in liver and oral cancers, however, all non-bone cancers were later downgraded – with a questionable rationale - by a government-review panel (Marcus 1990). In light of the importance of this study, EPA Professional Headquarters Union has requested that Congress establish an independent review to examine the study's results (Hirzy 2000).

27) A review of national cancer data in the US by the National Cancer Institute (NCI) revealed a significantly higher rate of bone cancer in young men in fluoridated versus unfluoridated areas (Hoover 1991). While the NCI concluded that fluoridation was not the cause, no explanation was provided to explain the higher rates in the fluoridated areas. A smaller study from New Jersey (Cohn 1992) found bone cancer rates to be up to 6 times higher in young men living in fluoridated versus unfluoridated areas. Other epidemiological studies have failed to find this relationship (Mahoney 1991; Freni 1992).

28) Fluoride administered to animals at high doses wreaks havoc on the male reproductive system - it damages sperm and increases the rate of infertility in a number of different species (Kour 1980; Chinoy 1989; Chinoy 1991; Susheela 1991; Chinoy 1994; Kumar 1994; Narayana 1994a, b; Zhao 1995; Elbetieha 2000; Ghosh 2002 and Zakrzewska 2002). While studies conducted at the FDA have failed to find reproductive effects in rats (Sprando 1996, 1997, 1998), an epidemiological study from the US has found increased rates of infertility among couples living in areas with 3 or more ppm fluoride in the water (Freni 1994), and 2 studies have found a reduced level of circulating testosterone in males living in high fluoride areas (Susheela 1996 and Barot 1998).

29) The fluoridation program has been very poorly monitored. There has never been a comprehensive analysis of the fluoride levels in the bones, blood, or urine of the American people or the citizens of other fluoridated countries. Based on the sparse data that has become available, however, it is increasingly evident that some people in the population – particularly people with kidney disease - are accumulating fluoride levels that have been associated with harm to both animals and humans, particularly harm to bone (see Connett 2004).

30) Once fluoride is put in the water it is impossible to control the dose each individual receives. This is because 1) some people (e.g. manual laborers, athletes, diabetics, and people with kidney disease) drink more water than others, and 2) we receive fluoride from sources other than the water supply. Other sources of fluoride include food and beverages processed with fluoridated water (Kiritsy 1996 and Heilman 1999), fluoridated dental products (Bentley 1999 and Levy 1999), mechanically deboned meat (Fein 2001), teas (Levy 1999), and pesticide residues on food (Stannard 1991 and Burgstahler 1997).

31) Fluoridation is unethical because individuals are not being asked for their informed consent prior to medication. This is standard practice for all medication, and one of the key reasons why most of western Europe has ruled against fluoridation (see appendix 2).

As one doctor aptly stated, "No physician in his right senses would prescribe for a person he has never met, whose medical history he does not know, a substance which is intended to create bodily change, with the advice: 'Take as much as you like, but you will take it for the rest of your life because some children suffer from tooth decay.’ It is a preposterous notion."

32) While referenda are preferential to imposed policies from central government, it still leaves the problem of individual rights versus majority rule. Put another way -- does a voter have the right to require that their neighbor ingest a certain medication (even if it's against that neighbor's will)?

33) Some individuals appear to be highly sensitive to fluoride as shown by case studies and double blind studies (Shea 1967, Waldbott 1978 and Moolenburg 1987). In one study, which lasted 13 years, Feltman and Kosel (1961) showed that about 1% of patients given 1 mg of fluoride each day developed negative reactions. Can we as a society force these people to ingest fluoride?

34) According to the Agency for Toxic Substances and Disease Registry (ATSDR 1993), and other researchers (Juncos & Donadio 1972; Marier & Rose 1977 and Johnson 1979), certain subsets of the population may be particularly vulnerable to fluoride's toxic effects; these include: the elderly, diabetics and people with poor kidney function. Again, can we in good conscience force these people to ingest fluoride on a daily basis for their entire lives?

35) Also vulnerable are those who suffer from malnutrition (e.g. calcium, magnesium, vitamin C, vitamin D and iodide deficiencies and protein poor diets) (Massler & Schour 1952; Marier & Rose 1977; Lin Fa-Fu 1991; Chen 1997; Teotia 1998). Those most likely to suffer from poor nutrition are the poor, who are precisely the people being targeted by new fluoridation programs. While being at heightened risk, poor families are less able to afford avoidance measures (e.g. bottled water or removal equipment).

36) Since dental decay is most concentrated in poor communities, we should be spending our efforts trying to increase the access to dental care for poor families. The real "Oral Health Crisis" that exists today in the United States, is not a lack of fluoride but poverty and lack of dental insurance. The Surgeon General has estimated that 80% of dentists in the US do not treat children on Medicaid.

37) Fluoridation has been found to be ineffective at preventing one of the most serious oral health problems facing poor children, namely, baby bottle tooth decay, otherwise known as early childhood caries (Barnes 1992 and Shiboski 2003).

38) The early studies conducted in 1945 -1955 in the US, which helped to launch fluoridation, have been heavily criticized for their poor methodology and poor choice of control communities (De Stefano 1954; Sutton 1959, 1960 and 1996; Ziegelbecker 1970). According to Dr. Hubert Arnold, a statistician from the University of California at Davis, the early fluoridation trials "are especially rich in fallacies, improper design, invalid use of statistical methods, omissions of contrary data, and just plain muddleheadedness and hebetude." In 2000, the British Government’s “York Review” could give no fluoridation trial a grade A classification – despite 50 years of research (McDonagh 2000, see Appendix 3 for commentary).

39) The US Public Health Service first endorsed fluoridation in 1950, before one single trial had been completed (McClure 1970)!

40) Since 1950, it has been found that fluorides do little to prevent pit and fissure tooth decay, a fact that even the dental community has acknowledged (Seholle 1984; Gray 1987; PHS 1993; and Pinkham 1999). This is significant because pit and fissure tooth decay represents up to 85% of the tooth decay experienced by children today (Seholle 1984 and Gray 1987).

41) Despite the fact that we are exposed to far more fluoride today than we were in 1945 (when fluoridation began), the "optimal" fluoridation level is still 1 part per million, the same level deemed optimal in 1945! (Marier & Rose 1977; Levy 1999; Rozier 1999 and Fomon 2000).

42) The chemicals used to fluoridate water in the US are not pharmaceutical grade. Instead, they come from the wet scrubbing systems of the superphosphate fertilizer industry. These chemicals (90% of which are sodium fluorosilicate and fluorosilicic acid), are classified hazardous wastes contaminated with various impurities. Recent testing by the National Sanitation Foundation suggest that the levels of arsenic in these chemicals are relatively high (up to 1.6 ppb after dilution into public water) and of potential concern (NSF 2000 and Wang 2000).

43) These hazardous wastes have not been tested comprehensively. The chemical usually tested in animal studies is pharmaceutical grade sodium fluoride, not industrial grade fluorosilicic acid. The assumption being made is that by the time this waste product has been diluted, all the fluorosilicic acid will have been converted into free fluoride ion, and the other toxics and radioactive isotopes will be so dilute that they will not cause any harm, even with lifetime exposure. These assumptions have not been examined carefully by scientists, independent of the fluoridation program.

44) Studies by Masters and Coplan (1999, 2000) show an association between the use of fluorosilicic acid (and its sodium salt) to fluoridate water and an increased uptake of lead into children's blood. Because of lead’s acknowledged ability to damage the child’s developing brain, this is a very serious finding yet it is being largely ignored by fluoridating countries.

45) Sodium fluoride is an extremely toxic substance -- just 200 mg of fluoride ion is enough to kill a young child, and just 3-5 grams (e.g. a teaspoon) is enough to kill an adult. Both children (swallowing tablets/gels) and adults (accidents involving fluoridation equipment and filters on dialysis machines) have died from excess exposure.

46) Some of the earliest opponents of fluoridation were biochemists and at least 14 Nobel Prize winners are among numerous scientists who have expressed their reservations about the practice of fluoridation (see appendix 4).

47) The recent Nobel Laureate in Medicine and Physiology, Dr. Arvid Carlsson (2000), was one of the leading opponents of fluoridation in Sweden, and part of the panel that recommended that the Swedish government reject the practice, which they did in 1971. According to Carlsson:

"I am quite convinced that water fluoridation, in a not-too-distant future, will be consigned to medical history...Water fluoridation goes against leading principles of pharmacotherapy, which is progressing from a stereotyped medication - of the type 1 tablet 3 times a day - to a much more individualized therapy as regards both dosage and selection of drugs. The addition of drugs to the drinking water means exactly the opposite of an individualized therapy" (Carlsson 1978).

48) While pro-fluoridation officials continue to promote fluoridation with undiminished fervor, they cannot defend the practice in open public debate – even when challenged to do so by organizations such as the Association for Science in the Public Interest, the American College of Toxicology, or the US Environmental Protection Agency (Bryson 2004). According to Dr. Michael Easley, a prominent lobbyist for fluoridation in the US, "Debates give the illusion that a scientific controversy exists when no credible people support the fluorophobics' view" (See appendix 5).

In light of proponents’ refusal to debate this issue, Dr. Edward Groth, a Senior Scientist at Consumers Union, observed that "the political profluoridation stance has evolved into a dogmatic, authoritarian, essentially antiscientific posture, one that discourages open debate of scientific issues" (Martin 1991).

49) Many scientists, doctors and dentists who have spoken out publicly on this issue have been subjected to censorship and intimidation (Martin 1991). Most recently, Dr. Phyllis Mullenix was fired from her position as Chair of Toxicology at Forsythe Dental Center for publishing her findings on fluoride and the brain; and Dr. William Marcus was fired from the EPA for questioning the government’s handling of the NTP’s fluoride-cancer study (Bryson 2004). Tactics like this would not be necessary if those promoting fluoridation were on secure scientific ground.

50) The Union representing the scientists at US EPA headquarters in Washington DC is now on record as opposing water fluoridation (Hirzy 1999). According to the Union’s Senior Vice President, Dr. William Hirzy:

"In summary, we hold that fluoridation is an unreasonable risk. That is, the toxicity of fluoride is so great and the purported benefits associated with it are so small - if there are any at all - that requiring every man, woman and child in America to ingest it borders on criminal behavior on the part of governments."

Conclusion

When it comes to controversies surrounding toxic chemicals, invested interests traditionally do their very best to discount animal studies and quibble with epidemiological findings. In the past, political pressures have led government agencies to drag their feet on regulating asbestos, benzene, DDT, PCBs, tetraethyl lead, tobacco and dioxins. With fluoridation we have had a fifty year delay. Unfortunately, because government officials have put so much of their credibility on the line defending fluoridation, and because of the huge liabilities waiting in the wings if they admit that fluoridation has caused an increase in hip fracture, arthritis, bone cancer, brain disorders or thyroid problems, it will be very difficult for them to speak honestly and openly about the issue. But they must, not only to protect millions of people from unnecessary harm, but to protect the notion that, at its core, public health policy must be based on sound science not political expediency. They have a tool with which to do this: it's called the Precautionary Principle. Simply put, this says: if in doubt leave it out. This is what most European countries have done and their children's teeth have not suffered, while their public's trust has been strengthened.

It is like a question from a Kafka play. Just how much doubt is needed on just one of the health concerns identified above, to override a benefit, which when quantified in the largest survey ever conducted in the US, amounts to less than one tooth surface (out of 128) in a child's mouth?

For those who would call for further studies, I say fine. Take the fluoride out of the water first and then conduct all the studies you want. This folly must end without further delay.


Postscript

Further arguments against fluoridation, can be viewed at http://www.fluoridealert.org. Arguments for fluoridation can be found at http://www.ada.org and a more systematic presentation of fluoride’s toxic effects can be found at http://www.Slweb.org/bibliography.html


Acknowledgements

I would like to acknowledge the help given to me in the research for this statement to my son Michael Connett and to Naomi Flack for the proofreading of the text. Any remaining mistakes are my own.


APPENDIX 1. World Health Organization Data

DMFT (Decayed, Missing & Filled teeth) Status for 12 year olds by Country
  DMFTs Year Status*
Australia 0.8 1998 More than 50% of water is fluoridated
Zurich, Switzerland 0.84 1998 Water is unfluoridated, but salt is fluoridated
Netherlands 0.9 1992-93 No water fluoridation or salt fluoridation
Sweden 0.9 1999 No water fluoridation or salt fluoridation
Denmark 0.9 2001 No water fluoridation or salt fluoridation
UK (England & Wales) 0.9 1996-97 11% of water supplies are fluoridated
Ireland 1.1 1997 More than 50% of water is fluoridated
Finland 1.1 1997 No water fluoridation or salt fluoridation
Germany 1.2 2000 No water fluoridation, but salt fluoridation is common
US 1.4 1988-91 More than 50% of water is fluoridated
Norway 1.5 1998 No water fluoridation or salt fluoridation
Iceland 1.5 1996 No water fluoridation or salt fluoridation
New Zealand 1.5 1993 More than 50% of water is fluoridated
Belgium 1.6 1998 No water fluoridation, but salt fluoridation is common
Austria 1.7 1997 No water fluoridation, but salt fluoridation is common
France 1.9 1998 No water fluoridation, but salt fluoridation is common
Data from WHO Oral Health Country/Area Profile Programme Department of Noncommunicable Diseases Surveillance/Oral Health WHO Collaborating Centre, Malmö University, Sweden http://www.whocollab.od.mah.se/euro.html

APPENDIX 2. Statements on fluoridation by governmental officials from several countries

Germany: "Generally, in Germany fluoridation of drinking water is forbidden. The relevant German law allows exceptions to the fluoridation ban on application. The argumentation of the Federal Ministry of Health against a general permission of fluoridation of drinking water is the problematic nature of compuls[ory] medication." (Gerda Hankel-Khan, Embassy of Federal Republic of Germany, September 16, 1999). www.fluoridealert.org/germany.jpeg

France: "Fluoride chemicals are not included in the list [of 'chemicals for drinking water treatment']. This is due to ethical as well as medical considerations." (Louis Sanchez, Directeur de la Protection de l'Environment, August 25, 2000). www.fluoridealert.org/france.jpeg

Belgium: "This water treatment has never been of use in Belgium and will never be (we hope so) into the future. The main reason for that is the fundamental position of the drinking water sector that it is not its task to deliver medicinal treatment to people. This is the sole responsibility of health services." (Chr. Legros, Directeur, Belgaqua, Brussels, Belgium, February 28, 2000). www.fluoridation.com/c-belgium.htm

Luxembourg: "Fluoride has never been added to the public water supplies in Luxembourg. In our views, the drinking water isn't the suitable way for medicinal treatment and that people needing an addition of fluoride can decide by their own to use the most appropriate way, like the intake of fluoride tablets, to cover their [daily] needs." (Jean-Marie RIES, Head, Water Department, Administration De L'Environment, May 3, 2000). www.fluoridealert.org/luxembourg.jpeg

Finland: "We do not favor or recommend fluoridation of drinking water. There are better ways of providing the fluoride our teeth need." (Paavo Poteri, Acting Managing Director, Helsinki Water, Finland, February 7, 2000). www.fluoridation.com/c-finland.htm

"Artificial fluoridation of drinking water supplies has been practiced in Finland only in one town, Kuopio, situated in eastern Finland and with a population of about 80,000 people (1.6% of the Finnish population). Fluoridation started in 1959 and finished in 1992 as a result of the resistance of local population. The most usual grounds for the resistance presented in this context were an individual's right to drinking water without additional chemicals used for the medication of limited population groups. A concept of "force-feeding" was also mentioned.

Drinking water fluoridation is not prohibited in Finland but no municipalities have turned out to be willing to practice it. Water suppliers, naturally, have always been against dosing of fluoride chemicals into water." (Leena Hiisvirta, M.Sc., Chief Engineer, Ministry of Social Affairs and Health, Finland, January 12, 1996.) www.fluoridealert.org/finland.jpeg

Denmark: "We are pleased to inform you that according to the Danish Ministry of Environment and Energy, toxic fluorides have never been added to the public water supplies. Consequently, no Danish city has ever been fluoridated." (Klaus Werner, Royal Danish Embassy, Washington DC, December 22, 1999). www.fluoridation.com/c-denmark.htm

Norway: "In Norway we had a rather intense discussion on this subject some 20 years ago, and the conclusion was that drinking water should not be fluoridated." (Truls Krogh & Toril Hofshagen, Folkehelsa Statens institutt for folkeheise (National Institute of Public Health) Oslo, Norway, March 1, 2000). www.fluoridation.com/c-norway.htm

Sweden: "Drinking water fluoridation is not allowed in Sweden...New scientific documentation or changes in dental health situation that could alter the conclusions of the Commission have not been shown." (Gunnar Guzikowski, Chief Government Inspector, Livsmedels Verket -- National Food Administration Drinking Water Division, Sweden, February 28, 2000). www.fluoridation.com/c-sweden.htm

Netherlands: "From the end of the 1960s until the beginning of the 1970s drinking water in various places in the Netherlands was fluoridated to prevent caries. However, in its judgement of 22 June 1973 in case No. 10683 (Budding and co. versus the City of Amsterdam) the Supreme Court (Hoge Road) ruled there was no legal basis for fluoridation. After that judgement, amendment to the Water Supply Act was prepared to provide a legal basis for fluoridation. During the process it became clear that there was not enough support from Parlement [sic] for this amendment and the proposal was withdrawn." (Wilfred Reinhold, Legal Advisor, Directorate Drinking Water, Netherlands, January 15, 2000). www.fluoridation.com/c-netherlands.htm

Northern Ireland: "The water supply in Northern Ireland has never been artificially fluoridated except in 2 small localities where fluoride was added to the water for about 30 years up to last year. Fluoridation ceased at these locations for operational reasons. At this time, there are no plans to commence fluoridation of water supplies in Northern Ireland." (C.J. Grimes, Department for Regional Development, Belfast, November 6, 2000). www.fluoridealert.org/Northern-Ireland.jpeg

Austria: "Toxic fluorides have never been added to the public water supplies in Austria." (M. Eisenhut, Head of Water Department, Osterreichische Yereinigung fur das Gas-und Wasserfach Schubertring 14, A-1015 Wien, Austria, February 17, 2000). www.fluoridation.com/c-austria.htm

Czech Republic:"Since 1993, drinking water has not been treated with fluoride in public water supplies throughout the Czech Republic. Although fluoridation of drinking water has not actually been proscribed it is not under consideration because this form of supplementation is considered as follows:

(a) uneconomical (only 0.54% of water suitable for drinking is used as such; the remainder is employed for hygiene etc. Furthermore, an increasing amount of consumers (particularly children) are using bottled water for drinking (underground water usually with fluor)

(b) unecological (environmental load by a foreign substance)

(c) unethical ("forced medication")

(d) toxicologically and phyiologically debateable (fluoridation represents an untargeted form of supplementation which disregards actual individual intake and requirements and may lead to excessive health-threatening intake in certain population groups; [and] complexation of fluor in water into non biological active forms of fluor." (Dr. B. Havlik, Ministerstvo Zdravotnictvi Ceske Republiky, October 14, 1999). www.fluoridealert.org/czech.jpeg


APPENDIX 3. Statement of Douglas Carnall, Associate Editor of the British Medical Journal, published on the BMJ website (http://www.bmj.com ) on the day that they published the York Review on Fluoridation.

See this review on the web at http://bmj.bmjjournals.com/cgi/content/full/321/7265/904/a

British Medical Journal, October 7, 2000, Reviews, Website of the week: Water fluoridation

Fluoridation was a controversial topic even before Kubrick's Base Commander Ripper railed against "the international communist conspiracy to sap and impurify all of our precious bodily fluids" in the 1964 film Dr Strangelove. This week's BMJ shouldn't precipitate a global holocaust, but it does seem that Base Commander Ripper may have had a point. The systematic review published this week (p 855) shows that much of the evidence for fluoridation was derived from low quality studies, that its benefits may have been overstated, and that the risk to benefit ratio for the development of the commonest side effect (dental fluorosis, or mottling of the teeth) is rather high.

Supplementary materials are available on the BMJ 's website and on that of the review's authors, enhancing the validity of the conclusions through transparency of process. For example, the "frequently asked questions" page of the site explains who comprised the advisory panel and how they were chosen ("balanced to include those for and against, as well as those who are neutral"), and the site includes the minutes of their meetings. You can also pick up all 279 references in Word97 format, and tables of data in PDF. Such transparency is admirable and can only encourage rationality of debate.

Professionals who propose compulsory preventive measures for a whole population have a different weight of responsibility on their shoulders than those who respond to the requests of individuals for help. Previously neutral on the issue, I am now persuaded by the arguments that those who wish to take fluoride (like me) had better get it from toothpaste rather than the water supply (see www.derweb.co.uk/bfs/index.html and www.npwa.freeserve.co.uk/index.html for the two viewpoints).

Douglas Carnall
Associate Editor
British Medical Journal


APPENDIX 4. List of 14 Noble Prize winners who have opposed or expressed reservations about fluoridation.

1) Adolf Butenandt (Chemistry, 1939)
2) Arvid Carlsson (Medicine, 2000)
3) Hans von Euler-Chelpin (Chemistry, 1929).
4) Walter Rudolf Hess (Medicine, 1949)
5) Corneille Jean-François Heymans (Medicine, 1938)
6) Sir Cyril Norman Hinshelwood (Chemistry, 1956)
7) Joshua Lederberg (Medicine, 1958)
8) William P. Murphy (Medicine, 1934)
8) Giulio Natta (1963 Nobel Prize in Chemistry)
10) Sir Robert Robinson (Chemistry, 1947)
11) Nikolai Semenov (Chemistry, 1956)
12) James B. Sumner (Chemistry, 1946)
13) Hugo Theorell (Medicine, 1955)
14) Artturi Virtanen (Chemistry, 1945)


APPENDIX 5. Quotes on debating fluoridation from Dr. Michael Easley, Director of the National Center for Fluoridation Policy and Research, and one of the most active proponents of fluoridation in the US (Easley 1999). Easley’s quotes typify the historic contempt that proponents have had to scientific debate.

"A favorite tactic of the fluorophobics is to argue for a debate so that 'the people can decide who is right.' Proponents of fluoride are often trapped into consenting to public debates."

"Debates give the illusion that a scientific controversy exists when no credible people support the fluorophobics' view."

"Like parasites, opponents steal undeserved credibility just by sharing the stage with respected scientists who are there to defend fluoridation"; and,

"Unfortunately, a most flagrant abuse of the public trust occasionally occurs when a physician or a dentist, for whatever personal reason, uses their professional standing in the community to argue against fluoridation, a clear violation of professional ethics, the principles of science and community standards of practice."


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Seppa L, et al. (2000). Caries trends 1992-98 in two low-fluoride Finnish towns formerly with and without fluoride. Caries Research 34: 462-8.

Shao Q, et al. (2000). [Influence of free radical inducer on the level of oxidative stress in brain of rats with fluorosis]. Zhonghua Yu Fang Yi Xue Za Zhi 34(6):330-2.

Shashi A. (2003). Histopathological investigation of fluoride-induced neurotoxicity in rabbits. Fluoride 36: 95-105.

Shea JJ, et al. (1967). Allergy to fluoride. Annals of Allergy 25:388-91.

Sheth FJ, et al. (1994). Sister chromatid exchanges: A study in fluorotic individuals of North Gujurat. Fluoride 27: 215-219.

Shiboski CH, et al. (2003). The association of early childhood caries and race/ethnicity among California preschool children. Journal of Public Health Dentistry 63:38-46.

Shivarajashankara YM , et al. (2002). Brain lipid peroxidation and antioxidant systems of young rats in chronic fluoride intoxication. Fluoride 35: 197-203.

Shivarajashankara YM , et al. (2002). Histological changes in the brain of young fluoride-intoxicated rats. Fluoride 35: 12-21.

Singh A, Jolly SS. (1970). Fluorides and Human Health. World Health Organization. pp 239-240.

Singh A, et al. (1963). Endemic fluorosis: epidemiological, clinical and biochemical study of chronic fluoride intoxication in Punjab. Medicine 42: 229-246.

Sprando RL, et al. (1998). Testing the potential of sodium fluoride to affect spermatogenesis: a morphometric study. Food and Chemical Toxicology 36: 1117-24.

Sprando RL, et al. (1997). Testing the potential of sodium fluoride to affect spermatogenesis in the rat. Food and Chemical Toxicology 35: 881-90.

Sprando RL, et al. (1996). Effect of intratesticular injection of sodium fluoride on spermatogenesis. Food and Chemical Toxicology 34: 377-84.

Stannard JG, et al. (1991). Fluoride Levels and Fluoride Contamination of Fruit Juices. Journal of Clinical Pediatric Dentistry 16: 38-40.

Stecher P, et al. (1960). The Merck Index of Chemicals and Drugs. Merck & Co., Inc, Rathway NJ. p. 952.

Steelink C. (1992). Fluoridation controversy. Chemical & Engineering News (Letter). July 27: 2-3.

Strunecka A, Patocka J. (1999). Pharmacological and toxicological effects of aluminofluoride complexes. Fluoride 32: 230-242.

Sun ZR, et al. (2000). Effects of high fluoride drinking water on the cerebral functions of mice. Chinese Journal of Epidemiology 19: 262-263.

Susheela AK. (1993). Prevalence of endemic fluorosis with gastrointestinal manifestations in people living in some North-Indian villages. Fluoride 26: 97-104.

Susheela AK, Kumar A. (1991). A study of the effect of high concentrations of fluoride on the reproductive organs of male rabbits, using light and scanning electron microscopy. Journal of Reproductive Fertility 92: 353-60.

Sutton P. (1996). The Greatest Fraud: Fluoridation. Lorne, Australia: Kurunda Pty, Ltd.

Sutton P. (1960) Fluoridation: Errors and Omissions in Experimental Trials. Melbourne University Press. Second Edition.

Sutton, P. (1959). Fluoridation: Errors and Omissions in Experimental Trials. Melbourne University Press. First Edition.

Teotia M, et al. (1998). Endemic chronic fluoride toxicity and dietary calcium deficiency interaction syndromes of metabolic bone disease and deformities in India: year 2000. Indian Journal of Pediatrics 65: 371-81.

Teotia SPS, Teotia M. (1994). Dental caries: a disorder of high fluoride and low dietary calcium interactions (30 years of personal research). Fluoride 27: 59-66.

Teotia SPS, et al. (1976). Symposium on the non-skeletal phase of chronic fluorosis: The Joints. Fluoride 9: 19-24.

Tsutsui T, Suzuki N, Ohmori M, Maizumi H. (1984). Cytotoxicity, chromosome aberrations and unscheduled DNA synthesis in cultured human diploid fibroblasts induced by sodium fluoride. Mutation Research 139:193-8.

Waldbott GL, et al. (1978). Fluoridation: The Great Dilemma. Coronado Press, Inc., Lawrence, Kansas.

Waldbott GL. (1965). A Battle with Titans. Carlton Press, NY.

Wang C, et al. (2000). Treatment Chemicals contribute to Arsenic Levels. Opflow (a journal of the American Water Works Association). October 2000.

Wang Y, et al. (1997). [Changes of coenzyme Q content in brain tissues of rats with fluorosis]. Zhonghua Yu Fang Yi Xue Za Zhi 31: 330-3.

WHO (Online). WHO Oral Health Country/Area Profile Programme. Department of Noncommunicable Diseases Surveillance/Oral Health. WHO Collaborating Centre, Malmö University, Sweden. http://www.whocollab. od.mah.se/euro.html

Williams JE, et al. (1990). Community water fluoride levels, preschool dietary patterns, and the occurrence of fluoride enamel opacities. Journal of Public Health Dentistry 50: 276-81.

Wu DQ, Wu Y. (1995). Micronucleus and sister chromatid exchange frequency in endemic fluorosis. Fluoride 28: 125-127.

Xiang Q, et al. (2003a). Effect of fluoride in drinking water on children's intelligence. Fluoride 36: 84-94.

Xiang Q. (2003b). Blood lead of children in Wamiao-Xinhuai intelligence study. Fluoride 36: 138.

Zakrzewska H, et al. (2002). In vitro influence of sodium fluoride on ram semen quality and enzyme activities. Fluoride 35: 153-160.

Zhai JX, et al. (2003). [Studies on fluoride concentration and cholinesterase activity in rat hippocampus]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 21: 102-4.

Zhang Z, et al. (2001). [Effects of selenium on the damage of learning-memory ability of mice induced by fluoride]. Wei Sheng Yan Jiu 30: 144-6.

Zhang Z, et al. (1999). [Effect of fluoride exposure on synaptic structure of brain areas related to learning-memory in mice] [Article in Chinese]. Wei Sheng Yan Jiu 28:210-2.

Zhao XL, Wu JH. (1998). Actions of sodium fluoride on acetylcholinesterase activities in rats. Biomedical and Environmental Sciences 11: 1-6.

Zhao LB, et al (1996). Effect of high-fluoride water supply on children's intelligence. Fluoride 29: 190-192.

Zhao ZL, et al. (1995). The influence of fluoride on the content of testosterone and cholesterol in rat. Fluoride 28: 128-130.

Ziegelbecker R. (1970). A critical review on the fluorine caries problem. Fluoride 3: 71-79.

The 19 studies on the possible association of hip fracture and fluoridated-water.

a) Studies Reporting an Association between fluoridated water (1 ppm fluoride) & hip fracture.

1 a) Cooper C, et al. (1990). Water fluoride concentration and fracture of the proximal femur. Journal of Epidemiology and Community Health 44: 17-19.

1 b) Cooper C, et al. (1991). Water fluoridation and hip fracture. JAMA 266: 513-514 (letter, a reanalysis of data presented in 1990 paper).

2) Danielson C, et al. (1992). Hip fractures and fluoridation in Utah's elderly population. Journal of the American Medical Association 268: 746-748.

3) Hegmann KT, et al. (2000). The Effects of Fluoridation on Degenerative Joint Disease (DJD) and Hip Fractures. Abstract #71, of the 33rd Annual Meeting of the Society For Epidemiological research, June 15-17, 2000. Published in a Supplement of American Journal of Epidemiology P. S18.

4) Jacobsen SJ, et al. (1992). The association between water fluoridation and hip fracture among white women and men aged 65 years and older; a national ecologic study." Annals of Epidemiology 2: 617-626.

5) Jacobsen SJ, et al. (1990). Regional variation in the incidence of hip fracture: US white women aged 65 years and olders. JAMA 264(4): 500-2.

6 a) Jacqmin-Gadda H, et al. (1995). Fluorine concentration in drinking water and fractures in the elderly. JAMA 273: 775-776 (letter).

6 b) Jacqmin-Gadda H, et al. (1998). Risk factors for fractures in the elderly. Epidemiology 9(4): 417-423. (An elaboration of the 1995 study referred to in the JAMA letter).

7) Keller C. (1991) Fluorides in drinking water. Unpublished results. Discussed in Gordon, S.L. and Corbin, S.B,(1992) Summary of Workshop on Drinking Water Fluoride Influence on Hip Fracture on Bone Health. Osteoporosis International 2: 109-117.

8) Kurttio PN, et al. (1999). Exposure to natural fluoride in well water and hip fracture: A cohort analysis in Finland. American Journal of Epidemiology 150(8): 817-824.

9) May DS, Wilson MG. (1992). Hip fractures in relation to water fluoridation: an ecologic analysis. Unpublished data, discussed in Gordon SL, and Corbin SB. (1992). Summary of Workshop on Drinking Water Fluoride Influence on Hip Fracture on Bone Health. Osteoporosis International 2:109-117.

b) Studies reporting an association between water-fluoride levels higher than fluoridated water (4 ppm+) & hip fracture.

Li Y, et al. (2001). Effect of long-term exposure to fluoride in drinking water on risks of bone fractures. Journal of Bone and Mineral Research 16: 932-9.

Sowers M, et al. (1991). A prospective study of bone mineral content and fracture in communities with differential fluoride exposure. American Journal of Epidemiology 133: 649-660.

c) Studies Reporting No Association between water fluoride & hip fracture:

(Note that in 4 of these 8 studies, an association was actually found between fluoride and some form of fracture – e.g. wrist and hip. See notes and quotes below.)

Cauley J. et al. (1995). Effects of fluoridated drinking water on bone mass and fractures: the study of osteoporotic fractures. Journal of Bone and Mineral Research 10: 1076-86.

Feskanich D, et al. (1998). Use of toenail fluoride levels as an indicator for the risk of hip and forearm fractures in women. Epidemiology 9: 412-6.

While this study didn't find an association between water fluoride and hip fracture, it did find an association - albeit non-significant 1.6 (0.8-3.1) - between fluoride exposure and elevated rates of forearm fracture.

Hillier S, et al. (2000). Fluoride in drinking water and risk of hip fracture in the UK: a case control study. The Lancet 335: 265-2690.

Jacobsen SJ, et al. (1993). Hip Fracture Incidence Before and After the Fluoridation of the Public Water Supply, Rochester, Minnesota. American Journal of Public Health 83: 743-745.

Karagas MR, et al. (1996). Patterns of Fracture among the United States Elderly: Geographic and Fluoride Effects. Annals of Epidemiology 6: 209-216.

As with Feskanich (1998) this study didn't find an association between fluoridation & hip fracture, but it did find an association between fluoridation and distal forearm fracture, as well as proximal humerus fracture. "Independent of geographic effects, men in fluoridated areas had modestly higher rates of fractures of the distal forearm and proximal humerus than did men in nonfluoridated areas."

Lehmann R, et al. (1998). Drinking Water Fluoridation: Bone Mineral Density and Hip Fracture Incidence. Bone 22: 273-278.

Phipps KR, et al. (2000). Community water fluoridation, bone mineral density and fractures: prospective study of effects in older women. British Medical Journal 321: 860-4.

As with Feskanich (1998) and Karagas (1996), this study didn't find an association between water fluoride & hip fracture, but it did find an association between water fluoride and other types of fracture - in this case, wrist fracture. "There was a non-significant trend toward an increased risk of wrist fracture."

Suarez-Almazor M, et al. (1993). The fluoridation of drinking water and hip fracture hospitalization rates in two Canadian communities. American Journal of Public Health 83: 689-693.

While the authors of this study conclude there is no association between fluoridation and hip fracture, their own data reveals a statistically significant increase in hip fracture for men living in the fluoridated area. According to the authors, "although a statistically significant increase in the risk of hip fracture was observed among Edmonton men, this increase was relatively small (RR=1.12)."

Fluoridation / Fluoride

Toxic Chemicals In Your Water

 

Fluoride compounds which are put in water (fluoridation), toothpaste and supplement tablets (including some vitamins) were never tested for safety before approval. Recent independent research by scientists not associated with dental trade organizations has shown the following:

  1. Neurotoxic and Lowers IQ
    In 1995, neurotoxicologist and former Director of toxicology at Forsyth Dental Center in Boston, Dr. Phyllis Mullenix published research showing that fluoride built up in the brains of animals when exposed to moderate levels. Damage to the brain occured and the behavior patterns of the animals was adversely effected. Offspring of pregnant animals receiving relatively low doses of fluoride showed permanent effects to the brain which were seen as hyperactivity (ADD-like symptoms). Young animals and adult animals given fluoride experienced the opposite effect -- hypoactivity or sluggishness. The toxic effects of fluoride on the central nervous system was subsequently confirmed by previously-classified government research. Two new epidemiological studies which tend to confirm fluoride's neurotoxic effects on the brain have shown that children exposed to higher levels of fluoride had lower IQs.
  2. A study published in Brain Research shows that rats drinking only 1 part per million fluoride (NaF) in water had histologic lesions in their brain similar to Alzheimer's disease and dementia. In addition, evidence was seen pointing to possible damage to the blood brain barrier from extended fluoride exposure. This study was the third in a series of papers published by Varner et al. Brain Research Vol. 784 No. 12 p 284-298 (1998). Results of this recent study and other studies showing significant dangers from low-level fluoride exposure were presented at a recent scientific symposium.
  3. Causes Cancer
    The Department of Health in New Jersey found that bone cancer in male children was between two and seven times greater in areas where water was fluoridated. U.S. Environmental Protection Agency (EPA) researchers confirmed the bone cancer-causing effects of fluoride at low levels in an animal model. A new study has shown that fluoridation of water is linked to uterine cancer deaths.
  4. Changes Bone Structure and Strength
    Fluoride gradually builds up in the bones and causes adverse changes to the bone structure. Quite a few studies have shown that fluoridation leads to increases in hip fractures. The tensile strength of the hip is destroyed over time by fluoride ingestion.
  5. Causes Birth Defects and Perinatal Deaths
    A toxicologist in the United Kingdom recently found that perinatal deaths in a fluoridated area was 15% higher than in neighboring non-fluoridated areas. The fluoridated area had a higher socio-economic status and would have been expected to have less perinatal deaths. The fluoridated area also had a 30% higher rate of Down's Syndrome. Chile banned fluoridation because of research by the world-reknowned researcher, Dr Albert Schatz, which showed a link to infant deaths due to fluoridation.
  6. Proven Ineffective
    Fluoride compounds in water and in supplements do not provide any significant cavity-protecting effects. All of the recent large-scale studies of water fluoridation have shown that there are no positive effects. That is why countries without fluoridation have shown an equal improvement in dental health as those with fluoridation. (See Research Item #5.) There is scientific evidence that excessive fluoride exposure leads to increased levels of caries. Even pro-fluoridation scientists admit that there is not any properly-conducted research showing that fluoride supplements help prevent cavities. (Note: check vitamins carefully to be sure they do not include fluoride.)
  7. Impairs Immune System
    Independent research has shown that fluoride impairs the functioning of the immune system. In the United States, where toxic fluoride compounds are regularly added to water and given to children since the 1960s and 1970s, we are beginning to see an overwhelming number of people of that generation who are developing chronic immune system disorders.
  8. Causes Acute Adverse Reactions
    Several double-blind studies have shown that fluoridated water can often cause acute adverse reactions (in addition to the chronic poisoning effects discussed below). Some of the effects seen in double-blind studies include: gastrointestinal symptoms, stomatitis, joint pains, polydipsia, headaches, visual disturbances, muscular weakness, and extreme tiredness. An enlightening review of a book by one famous and well-respected researcher from The Netherlands who found adverse reactions in double-blind experiments can be read here.
  9. Causes Initial Stages of Skeletal Fluorosis
    Fluoride can cause severe skeletal fluorosis at high levels. Chronic, long-term exposure to levels of fluoride commonly found in water and food in the U.S. can cause the beginning stages of skeletal fluorosis including: pains in bones and joints, sensations of burning, pricking, and tingling in the limbs, muscle weakness, chronic fatigue, gastrointestinal disorders, reduced appetite, backache, osteoarthritis, etc. In fact, decades of ingestion of fluoride from water and other common sources can be expected to cause these symptoms in large numbers of people based on calculations of fluoride intake and excretion. (Keep in mind that fluoride is a cumulative poison since it builds up in the body of years.) Very few healthcare practitioners are capable of diagnosing such a condition because healthcare practitioners are not trained to test for or recognize the effects chronic poisoning from fluoride.
  10. Increases Lead and Arsenic Exposure
    Fluoride compounds put into water are often contaminated with lead, arsenic and radio nuclides since the fluoride compounds are toxic waste byproducts which largely come from pollution scrubbers of fertilizer plants. A study published in 2000 showed that the dumping of toxic silicofluoride compounds into water ("fluoridation") causes an increase in blood lead levels in children.
  11. Fluoride Causes Osteoarthritis
    In a study published in Rhuematology International in 2001, researchers found a link between fluoride exposure and the development of osteoarthritis. The level of exposure that caused osteoarthritis is common in the United States.
  12. Contributes to the Development of Repetitive Stress Injury
    A clinical study in New Zealand showed that fluoride ingestion may be a contributing factor in the development of Repetative Stress Injury (RSI) since such ingestion may encourage the development of apatite crystal formation. Elimination of fluoride plus regular supplementation of magnesium appeared to help RSI patients considerably.
  13. Causes Permanent Disfigurement of the Teeth in Many Children
    A very large and increasing number of children are experiencing dental fluorosis which is a permanent adverse structural change to the teeth.
  14. Inhibits Key Enzymes
    As fluoride builds up in different parts of the body over decades it can disrupt the actions of many key enzymes. This fact has been known for a long time.
  15. Supresses Thyroid Function
    Fluoride was given at low levels during the early to mid 20th century as an effective way of supressing thyroid function and treating hyperthyroidism. Articles and research can be found on the Thyroid web page.
  16. Causes Large Numbers of Acute Poisonings
    Fluoride is an extremely poisonous substances at exceptionally low doses and has caused a large number of acute poisonings. This is why a poison warning is now required on fluoridated toothpastes sold in the U.S.
  17. Independent Experts Oppose Dumping Fluoride Into Water
    Over 1500 professionals at the US EPA, including toxicologists and risk assessment experts voted unanimously to oppose the fluoridation initiative in California because of the health risks involved. See summary or official EPA union statement. Even the Candian Dental Association Consultant and Researcher urged people to avoid drinking fluoridated water.
  18. Unethical
    Fluoridation amounts to forced medication of the water supply. Such practices demonstrate a complete lack of ethics on the part of its promoters. Studies as early the 1930s showed extreme hazards to man and the environment due to fluoride dumping and exposure. Companies and organizations involved used the promotion of "fluoridation" as a way to avoid lawsuits due to dumping toxic wastes and later for economic gain. Please read the short history of fluoridation for more detailed information.
  19. Banned in Many Countries
    Fluoridation is not legal or not used in the overwhelming number of countries including industrialized countries. Please see Fluoride Status of Countries web page.

Many independent researchers, organizations, holistic healthcare experts and a growing number of dentists who avoid the use of toxic substances are warning their patients to avoid fluoridated water and fluoridated toothpaste and to definately not give children any fluoride since they appear to be more susceptible to the neurological toxicity from fluoride.

If your water department adds toxic fluoride compounds to the water, the best course of action is usually to drink and cook with bottled "spring" water. Carbon filters do not remove fluoride compounds to any significant extent. Avoid putting fluoridated water in humidifiers. Many non-organic juices have large amounts of fluoride from pesticide residues. It is best to juice your own vegetables and fruits from organic produce or go to a health food store to purchase organic juices.

Avoid toothpastes that have fluoride even if the manufacturers claim that the fluoride came from "natural" sources. Even though topical fluoride treatment may have an effect to help remineralize cavities at the early stages, the combination of a healthy diet, proper dental hygiene and saliva can have a similar effect. It is impossible to avoid swallowing some fluoride from fluoridated toothpaste. I have tried various toothpastes and current use the natural Weleda toothpaste with baking soda. I like that fact that it does not contain fluoride or the detergent, sodium lauryl sulfate (SLS).

More detailed information about fluoride and proper dental care:

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